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structure nameSTRUCTURAL BASIS FOR THYMINE GLYCOSYLASE ACTIVITY ON T:O6-METHYLG MISMATCH BY METHYL-CPG BINDING DOMAIN PROTEIN 4: IMPLICATIONS FOR ROLES OF ARG468 IN MISMATCH RECOGNITION AND CATALYSIS
(Methyl-CpG-binding domain protein 4)
referenceOuzon-Shubeita et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=1.55, R-factor=0.137)
structural superfamilyDNA-glycosylase;
redundant complexes4dk9_A 4e9f_A 4e9g_A 4e9h_A 4ea4_A 4ea5_A 4evv_A 4ew0_A 4ew4_A 4ofe_A 4ofh_A 6vjw_A 7kz0_A 7kz1_A 7kzg_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  NGRGTG----LG----LCRG------------                              +--------7kz0_A    
                                                  +-------------7 
  --QG--QG--YC--------------------   L            !             !    +---7ef9_A    
                                                  !             +----5 
  --QG--RG--YC--------------------                !                  +---6u7t_A    
                                               +-10  
  QGKGLGSGAG--SC--LTKC------------             !  !                     +-4b21_A    
                                               !  !                   +-3 
  --NG--RG------FGRC--------------             !  !            +------4 +-4ejy_A    
                                               !  !            !      ! 
  --NCNANARC----YGRC--------------          +-11  +------------8      +--2xhi_A    
                                            !  !               ! 
  ----------YG--------------------          !  !               +---------5kn8_A    
                                            !  !  
  NGRGTG----LG----LC--------------          !  !                  +------6vjw_A    
                                            !  +------------------6 
  --QTLAHGAT--------KT------------       +-12                     +------3s6i_A    
                                         !  !  
  --RT------------------NCSTNARG--   L   !  !                            +1mnm_C    
                                         !  !                          +-1 
  ----------------------ITQCNAACRG   L   !  !      +-------------------2 +6a8r_A    
                                       -13  !      !                   ! 
  ----------------------NT--NAIARG   L   !  +------9                   +-1b72_B    
                                         !         ! 
  --------------------RTVAITNAMCRG   L   !         +---------------------1yrn_A    
                                         !  
  ----------------------VAQTNA----   L   +-----------------------------1fjl_B    
                                       

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updated Fri Sep 13 18:34:06 2024