6nce_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN FOXN3 DNA BINDING DOMAIN IN COMPLEX WITH A FORKHEAD DNA SEQUENCE (Forkhead box protein N3)
reference	Hallworth et al. 'Mol. 74 245 2019
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
multimeric complexes	6ncm_AB
redundant complexes	6ncm_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6nce_A interface=50,51,53,54,57, gnckppysfsclifmaiedsptkrlpvkdiynwilehfpyfanaptgwkNSvRHnlSlnkcfkkvdkgslwcidpeyrqnliqalkktp
interface signature	NSRHS

Estimated binding specificities ?

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# IC=5.582 IC/col=0.930 n_of_columns=6

specificity:

A |   0  60  96  60   0  84
C |   0  12   0  12  96   0
G |   0  12   0  12   0  12
T |  96  12   0  12   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------------NAST--RGHT--STLT----   L                            +------7cby_C    
                                                                +-1 
  ------------NAST--RTHT--ST------   L                  +-------2 +------3l2c_A    
                                                        !       ! 
  RT--LA--TTETYTRG----------------   L          +-------3       +--------1f4k_B    
                                                !       ! 
  ------RGSTRTSTHG----------------   L        +-4       +----------------3zpl_B    
                                              ! ! 
  --TT----KATTQTTG----LTRT----KAFT   L     +--5 +------------------------2p7c_B    
                                           !  ! 
  ----------KT--RGAT--RGNT--------   L   +-6  +--------------------------8smh_F    
                                         ! ! 
  ----------SA--------------------     --7 +-----------------------------2xcr_U    
                                         ! 
  --------------------YG----------       +-----------------------------3eyi_B

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updated Fri Sep 13 22:41:51 2024