Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) IN COMPLEX WITH LSP
(Transcription factor A, mitochondrial)
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.70, R-factor=0.210)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes6erp_ACF 6erp_BGJ 6erq_ACF 6erq_BGJ 7lbw_AB
redundant complexes7lbw_B 6erp 6erq
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=11.960 IC/col=0.664 n_of_columns=18 specificity:   
A |  96   0  96   0  16  24  24  24  24  24  24   0   0  96  96  24   8  56
C |   0  96   0   0  16  24  24  24  24  24  24  96  96   0   0  24   8  16
G |   0   0   0  96   0  24  24  24  24  24  24   0   0   0   0  24   8   8
T |   0   0   0   0  64  24  24  24  24  24  24   0   0   0   0  24  72  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --STYGLCSGLAKTTGTCIGMGKGRTYANTVTFGPGQCLC   L                   +---------------7lbx_A    
                                                          +------1 
  RCNTFTMA--RAHGNAACST--------------------   L         +--2      +---------------4euw_A    
                                                       !  ! 
  RTNTFTMA--RT--NG--SA--------------------   L       +-3  +----------------------4y60_C    
                                                     ! ! 
  KCNT--MAMA--EGSAACNT--------------------   L     +-4 +-------------------------2lef_A    
                                                   ! ! 
  ------FTCA----IG--AT--------------------       +-5 +--------------------------6oem_H    
                                                 ! ! 
  RGNTFTMA--RT--NGRTSA--------------------   L --6 +---------------------------7m5w_A    
                                                 ! 
  ----YA--------FT--SG--------------------       +---------------------------5ze0_N

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updated Sat Sep 14 03:03:43 2024