7tdx_A : 3D-footprint complex

structure name	STRUCTURE OF FOXP3-DNA COMPLEX
reference	Leng et al. Immunity 55 1354 2022
experiment	X-ray (resolution=3.10, R-factor=0.299)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7tdx_A interface=62,65,66,69,70, peffhnmdyfkyhnmrppftyatlirwaileaperqrtlneiyhwftrmfayfrnhpatwkNaiRHnlSLhkcfvrvesekgavwtvdef
interface signature	NRHSL

Estimated binding specificities ?

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# IC=2.439 IC/col=0.407 n_of_columns=6

specificity:

A |   8  75  81  52  20  60
C |   8   7   4  16  34  12
G |   8   7   4  14  22  12
T |  72   7   7  14  20  12

scan!

Dendrogram of similar interfaces ?

matrix format

  
  KGQG----------------------                                       +-8h7a_A    
                                       +---------------------------1 
  --------TCTG--YTRT--------         +-2                           +-7vpz_N    
                                     ! ! 
  ------------KT----RGSTRGYC   L   +-3 +-----------------------------4uno_A    
                                   ! ! 
  ----FGTTPTRTAT----LT------   L --4 +-----------------------------4hqe_A    
                                   ! 
  ----DT--------RTRGTT--KT--   L   +-----------------------------2o8k_A

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updated Tue Dec 19 20:45:24 2023