interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF FOXP3-DNA COMPLEX
referenceLeng et al. Immunity 55 1354 2022
experimentX-ray (resolution=3.10, R-factor=0.299)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRHSL

Estimated binding specificities ?

contactlogo
# IC=2.439 IC/col=0.407 n_of_columns=6 specificity:   
A |   8  75  81  52  20  60
C |   8   7   4  16  34  12
G |   8   7   4  14  22  12
T |  72   7   7  14  20  12
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------NAST--RGHT--STLT------   L                          +------7cby_C    
                                                             +--1 
  --ST------NAST--RTHT--ST--------   L               +-------2  +------3l2c_A    
                                                     !       ! 
  ----RGSTRTSTHG------------------   L       +-------3       +---------3zpl_B    
                                             !       ! 
  TT----KATTQTTG----LTRT----KAFTYT   L   +---4       +-----------------2p7c_B    
                                         !   ! 
  --------KT--RGAT--RGNT----------   L --5   +-------------------------8smh_F    
                                         ! 
  ------------------YG------------       +-----------------------------3eyi_B    
                                       

home
updated Sat Sep 14 04:39:27 2024