7yz7_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ZEBRAFISH FOXH1 BOUND TO THE TGTGGATT SITE (Forkhead box protein H1)
reference	Macias et al. 'To ? ? 2022
source	Danio rerio
experiment	X-ray (resolution=0.98, R-factor=0.133)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
redundant complexes	7yza_A 7yzc_A 7yzd_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7yz7_A interface=1,3,5,54,55,57,58,59,61,79, KnYqRypkppysylamiamviqnspekkltlseilkeistlfpffkgnykgwrDSvRHNlSsydcfvkvlkdpgkpqgKgnfwtvevnriplellkrqntavsrqdetifaqdlapyifq
interface signature	KYRDSRHNSK

Estimated binding specificities ?

readout + contact

# IC=8.721 IC/col=0.969 n_of_columns=9

specificity:

A |  82  84   0   6   0  68   0  96  75
C |   6   6   0  75  96   6  96   0   6
G |   6   6   0   6   0  13   0   0   9
T |   2   0  96   9   0   9   0   0   6

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----------QTNAST--RGHTNTSTLA   L       +-----------------------------2hdc_A    
                                       +-2 
  --------KT----RGAT--RGYA----   L     ! !                             +1bc8_C    
                                     +-3 +-----------------------------1 
  --------KT----RG----RGYA----   L   ! !                               +1dux_F    
                                   --4 ! 
  YCKTHGSTQT--YTPT------------   L   ! +-----------------------------5x11_A    
                                     ! 
  --------KT----RG----RGYA----   L   +-----------------------------4lg0_B

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updated Wed Dec 20 00:20:46 2023