7yz7_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ZEBRAFISH FOXH1 BOUND TO THE TGTGGATT SITE (Forkhead box protein H1)
reference	Macias et al. 'To ? ? 2022
source	Danio rerio
experiment	X-ray (resolution=0.98, R-factor=0.133)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
redundant complexes	7yza_A 7yzc_A 7yzd_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7yz7_A interface=1,3,5,54,55,57,58,59,61,79, KnYqRypkppysylamiamviqnspekkltlseilkeistlfpffkgnykgwrDSvRHNlSsydcfvkvlkdpgkpqgKgnfwtvevnriplellkrqntavsrqdetifaqdlapyifq
interface signature	KYRDSRHNSK

Estimated binding specificities ?

readout + contact

# IC=9.982 IC/col=0.998 n_of_columns=10

specificity:

A |   5   0   0   5   0   7  96   1   2   5
C |   5   0   0   5   0   5   0   0   5  11
G |  13   0  96   0  96  79   0   5   5  67
T |  73  96   0  86   0   5   0  90  84  13

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------------NAST--RGHT--STLT--------   L                      +-------7cby_C    
                                                              +-1 
  ------------NAST--RTHT--ST----------   L             +------2 +-------3l2c_A    
                                                       !      ! 
  ----------RTSTHG--------------RA----   L     +-------3      +---------3zpl_B    
                                               !       ! 
  RT--LAHGTTETYTRG--------------------   L   +-4       +----------------1f4k_B    
                                             ! ! 
  --TT----KATTQTTG----LTRT----KA--FTYT   L --5 +------------------------2p7c_B    
                                             ! 
  ----------KT--RGAT--RGNT------------   L   +--------------------------8smh_F

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updated Sun Aug 3 21:56:21 2025