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structure nameCRYSTAL STRUCTURE OF THE ZEBRAFISH FOXH1 BOUND TO THE TGTGGATT SITE
(Forkhead box protein H1)
referenceMacias et al. 'To ? ? 2022
sourceDanio rerio
experimentX-ray (resolution=0.98, R-factor=0.133)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
redundant complexes7yza_A 7yzc_A 7yzd_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYRDSRHNSK

Estimated binding specificities ?

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# IC=8.681 IC/col=0.965 n_of_columns=9 specificity:   
A |  84  78   0   6   0  70   0  96  76
C |   6   6   0  76  96   8  96   0   6
G |   6   6   0   6   0  12   0   0   6
T |   0   6  96   8   0   6   0   0   8
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------------NAST--RGHT--STLT--------   L                       +------7cby_C    
                                                     +-----------1 
  ------------NAST--RTHT--ST----------   L       +---2           +------3l2c_A    
                                                 !   ! 
  ----------RTSTHG--------------RA----   L     +-3   +------------------3zpl_B    
                                               ! ! 
  RT--LAHGTTETYTRG--------------------   L   +-4 +----------------------1f4k_B    
                                             ! ! 
  --TT----KATTQTTG----LTRT----KA--FTYT   L --5 +------------------------2p7c_B    
                                             ! 
  ----------KT--RGAT--RGNT------------   L   +--------------------------8smh_F    
                                           

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updated Wed Dec 18 14:50:21 2024