interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE RESTRICTION-MODIFICATION CONTROLLER PROTEIN C.ESP1396I TETRAMER IN COMPLEX WITH ITS NATURAL 35 BASE-PAIR OPERATOR
(Regulatory protein)
referenceMcGeehan et al. 'Nucleic 36 4778 2008
sourceEnterobacter sp.
experimentX-ray (resolution=2.80, R-factor=0.209)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyHelixturnhelix;
multimeric complexes3clc_ABCD 3s8q_AB 3ufd_AB 4ivz_AF 4iwr_AB 4iwr_EF 4x4b_ABCD 4x4c_ABCD 4x4d_ABCD 4x4e_ABCD 4x4f_ABCD 4x4g_ABCD 4x4h_ABCD 4x4i_ABCD
reference complex3s8q_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQEDTYSRR

Estimated binding specificities ?

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# IC=5.379 IC/col=0.896 n_of_columns=6 specificity:   
A |   9   0   0   0  67   9
C |   9   0   0   0  11   9
G |   9  96   0  96   9   9
T |  69   0  96   0   9  69
scan!

Dendrogram of similar interfaces ?

matrix format
  
  QTEGDC--TAYTST--RG--RA--------   L                          +----3clc_C    
                                                       +------2 
  QT--STNTVTATSTQTRTETTT--------   L                   !      !   +2r1j_L    
                                                  +----4      +---1 
  --TT--QAQCSTQCLT----------RA--   L              !    !          +3cro_L    
                                               +--5    ! 
  ----TTQAQTSTEAQT--------------   L           !  !    +-----------1rpe_R    
                                           +---6  ! 
  --ET--QASG----------NG--------   L       !   !  +----------------1lmb_4    
                                           !   ! 
  QTET--QTSG----------NA--------   L       !   +-------------------3bdn_A    
                                       +---8 
  --STKCQAAT--SA----------------   L   !   !                +------3dnv_B    
                                       !   !   +------------3 
  ----TTQA--LTSAET--------------   L --9   +---7            +------2o4a_A    
                                       !       ! 
  ----------------------NGNT--RG   L   !       +-------------------1j3e_A    
                                       ! 
  QA--STQAST--SA----------------   L   +---------------------------3d1n_I    
                                     

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updated Thu Sep 12 17:00:57 2024