4bul_C : 3D-footprint complex

structure name	NOVEL HYDROXYL TRICYCLICS (E.G. GSK966587) AS POTENT INHIBITORS OF BACTERIAL TYPE IIA TOPOISOMERASES (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)
reference	Rittenhouse et al.
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=2.60, R-factor=0.145)
structural superfamily	Type II DNA topoisomerase;
sequence family	DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4bul_C interface=45,206,265,266,273,303,356, gkladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvRmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql
interface signature	KYSSRRI

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# IC=3.815 IC/col=0.477 n_of_columns=8

A |  17  24  24   8  11  24   0   0
C |   8  24  24  62   8  24  96   0
G |  28  24  24   0   8  24   0  96
T |  43  24  24  26  69  24   0   0

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updated Mon Dec 16 22:50:57 2024