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legend  pdf

structure nameCRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE HEXAPEPTIDE AND UBDA MOTIFS
(HOMEOTIC PROTEIN ULTRABITHORAX)
referenceOrtiz-Lombardia et al. Structure 23 270 2015
sourceDROSOPHILA MELANOGASTER
experimentX-ray (resolution=2.36, R-factor=0.213)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1b8i_AB 4cyc_AB 4uus_AB 4uus_EF
redundant complexes1b8i_A 4uus_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQNMK

Estimated binding specificities ?

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# IC=3.562 IC/col=0.890 n_of_columns=4 specificity:   
A |  19   0  96   0
C |  19  20   0   0
G |  19   0   0   0
T |  39  76   0  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT----IAQCNAMG----   L                             +---1b72_A    
                                                 +---4 
  RT--QTVAQTNA------   L                         !   !   +8osb_E    
                                                 !   +---1 
  RA----IAQTNA------   L                     +---5       +5ego_B    
                                             !   ! 
  RT----VTKGNA--KA--   L                     !   !     +-2lkx_A    
                                      +------6   +-----3 
  RT----NT--NA------   L              !      !         +-1b72_B    
                                      !      ! 
  ------NCICNARGRG--   L     +--------7      !          +4xrm_B    
                             !        !      +----------2 
  --RT--NT--NAIARG--   L     !        !                 +4cyc_B    
                           +-8        ! 
  RC----IAQCNAYC----   L   ! !        +------------------3rkq_B    
                         --9 ! 
  ------VTCCNAQA--RT   L   ! +---------------------------8g87_X    
                           ! 
  ------------YCFAKC   L   +---------------------------6pe2_B

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updated Sat Jan 10 06:56:24 2026