4cyc_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE HEXAPEPTIDE AND UBDA MOTIFS (HOMEOTIC PROTEIN ULTRABITHORAX)
reference	Ortiz-Lombardia et al. Structure 23 270 2015
source	DROSOPHILA MELANOGASTER
experiment	X-ray (resolution=2.36, R-factor=0.213)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1b8i_AB 4cyc_AB 4uus_AB 4uus_EF
redundant complexes	1b8i_A 4uus_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cyc_A interface=7,49,52,53,56,60, fypwmaRqtytryqtlelekefhtnhyltrrrriemahalclterqikIwfQNrrMklkKeiqaik
interface signature	RIQNMK

Estimated binding specificities ?

readout + contact

# IC=3.569 IC/col=0.892 n_of_columns=4

specificity:

A |  96   0  77  38
C |   0   0   0  19
G |   0   0  19  20
T |   0  96   0  19

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RT--IAQCNAMG----   L                          +---1b72_A    
                                        +-------2 
  RTQTVAQTNA------   L                  !       !   +8osb_E    
                                   +----3       +---1 
  RT--VTKGNA--KA--   L             !    !           +2lkx_A    
                           +-------4    ! 
  ----NCICNARGRG--   L     !       !    +-----------4xrm_B    
                         +-5       ! 
  RC--IAQCNAYC----   L   ! !       +----------------3rkq_B    
                       --6 ! 
  ----VTCCNAQA--RT   L   ! +------------------------8g87_X    
                         ! 
  ----------YCFAKC       +-------------------------6pe2_B

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updated Fri Sep 13 18:07:28 2024