4cyc_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE HEXAPEPTIDE AND UBDA MOTIFS (HOMEOTIC PROTEIN ULTRABITHORAX)
reference	Ortiz-Lombardia et al. Structure 23 270 2015
source	DROSOPHILA MELANOGASTER
experiment	X-ray (resolution=2.36, R-factor=0.213)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1b8i_AB 4cyc_AB 4uus_AB 4uus_EF
redundant complexes	1b8i_A 4uus_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4cyc_A interface=7,49,52,53,56,60, fypwmaRqtytryqtlelekefhtnhyltrrrriemahalclterqikIwfQNrrMklkKeiqaik
interface signature	RIQNMK

Estimated binding specificities ?

readout + contact

# IC=3.527 IC/col=0.882 n_of_columns=4

specificity:

A |  96   0  76  39
C |   0   0   1  19
G |   0   0  19  19
T |   0  96   0  19

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RT----IAQCNAMG----   L                           +---1b72_A    
                                                +--4 
  RT--QTVAQTNA------   L                        !  !   +8osb_E    
                                                !  +---1 
  RT----VTKGNA--KA--   L                        !      +2lkx_A    
                                  +-------------5 
  ------NCICNARGRG--   L          !             !        +4xrm_B    
                                  !             !      +-2 
  ------NCITNARGRG--   L     +----6             +------3 +6fqq_E    
                             !    !                    ! 
  --RT--NT--NAIARG--   L     !    !                    +4cyc_B    
                           +-7    ! 
  RC----IAQCNAYC----   L   ! !    +--------------------3rkq_B    
                         --8 ! 
  ------VTCCNAQA--RT   L   ! +-------------------------8g87_X    
                           ! 
  ------------YCFAKC   L   +--------------------------6pe2_B

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updated Mon Jun 29 17:44:23 2026