interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF S.A. GYRASE IN COMPLEX WITH COMPOUND 7
(DNA GYRASE SUBUNIT A AND B)
referenceSoisson et al. Bioorg.Med.Chem.Lett. 25 1831 2015
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=2.65, R-factor=0.172)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7fvs_AB 7fvt_AB 7mvs_AB
reference complex5npk_d
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKSRI

Estimated binding specificities ?

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# IC=3.142 IC/col=0.628 n_of_columns=5 specificity:   
A |   0   0  24  57  16
C |  96   0  24  13  13
G |   0  96  24  13  54
T |   0   0  24  13  13
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updated Thu Sep 12 20:50:42 2024