interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF S.A. GYRASE IN COMPLEX WITH COMPOUND 7
(DNA GYRASE SUBUNIT A AND B)
referenceSoisson et al. Bioorg.Med.Chem.Lett. 25 1831 2015
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=2.65, R-factor=0.172)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKSRI

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0   0  24  54  13
C |  96   0  24  16  13
G |   0  96  24  13  54
T |   0   0  24  13  16
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updated Tue Dec 17 01:09:23 2024