interface graph thumbnail
legend  pdf

structure nameTHE CRYSTAL STRUCTURE OF S. AUREUS GYRASE COMPLEX WITH ID-130 AND DNA
referenceGarofalo et al. J.Med.Chem. 62 7445 2019
experimentX-ray (resolution=2.70, R-factor=0.228)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKSRI

Estimated binding specificities ?

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# IC=3.968 IC/col=0.661 n_of_columns=6 specificity:   
A |   0   0  24  67  11   9
C |  96   0  24  11   9   9
G |   0  96  24   9  67  67
T |   0   0  24   9   9  11
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updated Tue Dec 17 04:04:41 2024