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structure nameCRYSTAL STRUCTURE OF S. AUREUS GYRASE IN COMPLEX WITH 4-[[1-[(1- CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[C]PYRIDIN-6-YL)METHYL]AZETIDIN-3- YL]METHYLAMINO]-6-FLUOROCHROMEN-2-ONE
reference'Acs 2023
experimentX-ray (resolution=2.16, R-factor=0.191)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7fvs_AB 7fvt_AB 7mvs_AB
reference complex5npk_d
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYRSSRI

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0   0  24  54  13
C |  96   0  24  13  13
G |   0  96  24  13  54
T |   0   0  24  16  16
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updated Fri Sep 13 04:04:46 2024