7fvs_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF S. AUREUS GYRASE IN COMPLEX WITH 4-[[1-[(1- CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[C]PYRIDIN-6-YL)METHYL]AZETIDIN-3- YL]METHYLAMINO]-6-FLUOROCHROMEN-2-ONE
reference	'Acs 2023
experiment	X-ray (resolution=2.16, R-factor=0.191)
structural superfamily	Type II DNA topoisomerase;
sequence family	DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7fvs_A interface=44,205,213,264,265,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql
interface signature	KYRSSRI

Estimated binding specificities ?

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# IC=4.002 IC/col=0.334 n_of_columns=12

specificity:

A |   0   0  24  24  12  24  24  24  12  24  24  86
C |  96   0  24  24  21  24  24  24  53  24  24   0
G |   0  96  24  24  42  24  24  24  10  24  24   0
T |   0   0  24  24  21  24  24  24  21  24  24  10

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updated Tue Dec 17 09:14:47 2024