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structure nameCRYSTAL STRUCTURE OF S. AUREUS GYRASE IN COMPLEX WITH 6-[5-[2-[(4- CHLORO-2,3-DIHYDRO-1H-INDEN-2-YL)METHYLAMINO]ETHYL]-2-OXO-1,3- OXAZOLIDIN-3-YL]-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE
reference'Acs 2023 X-RAY DIFFRACTION
experimentX-ray (resolution=2.08, R-factor=0.202)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7fvs_AB 7fvt_AB 7mvs_AB
reference complex5npk_d
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKYSSRI

Estimated binding specificities ?

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# IC=4.434 IC/col=0.369 n_of_columns=12 specificity:   
A |   0  24  24  24  24  24  16  13  24  24   0   0
C |   0  24  24  24  24  24  54  54  24  24  96   0
G |   0  24  24  24  24  24  13  13  24  24   0  96
T |  96  24  24  24  24  24  13  16  24  24   0   0
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updated Fri Sep 13 04:05:06 2024