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structure nameTHE CRYSTAL STRUCTURE OF HUMAN FORKHEAD BOX PROTEIN IN COMPLEX WITH DNA 1
(Forkhead box protein L2)
referenceYoon et al. 'Nucleic 50 8929 2022
sourceHomo sapiens
experimentX-ray (resolution=3.10, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes7vov_AB
redundant complexes7vov_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHNSLK

Estimated binding specificities ?

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# IC=4.897 IC/col=0.816 n_of_columns=6 specificity:   
A |  20  20  13   0   0  96
C |   0  13  13   0   6   0
G |  13  57   9   0   0   0
T |  63   6  61  96  90   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------NAST--RGHT--STLT--------   L                       +------7cby_C    
                                                       +-----------1 
  --------------NAST--RTHT--ST----------   L       +---2           +------3l2c_A    
                                                   !   ! 
  RT--LANTHGTTETYTRG--------------------   L     +-3   +------------------1f4k_B    
                                                 ! ! 
  --------RGSTRTSTHG--------------RA----   L   +-4 +----------------------3zpl_B    
                                               ! ! 
  --TT------KATTQTTG----LTRT----KA--FTYT   L --5 +------------------------2p7c_B    
                                               ! 
  ------------KT--RGAT--RGNT------------   L   +--------------------------8smh_F

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updated Wed Dec 18 13:35:08 2024