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legend  pdf

structure nameTHE CRYSTAL STRUCTURE OF HUMAN FORKHEAD BOX PROTEIN IN COMPLEX WITH DNA 1
(Forkhead box protein L2)
referenceYoon et al. 'Nucleic 50 8929 2022
sourceHomo sapiens
experimentX-ray (resolution=3.10, R-factor=0.227)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes7vov_AB
redundant complexes7vov_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHNSLK

Estimated binding specificities ?

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# IC=4.673 IC/col=0.779 n_of_columns=6 specificity:   
A |   0  96  96  54  14  53
C |   0   0   0  14  54  14
G |   0   0   0  14  14  22
T |  96   0   0  14  14   7
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------NAST--RGHT--STLT--------   L                      +-------7cby_C    
                                                                +-1 
  --------------NAST--RTHT--ST----------   L             +------2 +-------3l2c_A    
                                                         !      ! 
  --------RGSTRTSTHG--------------RA----   L         +---3      +---------3zpl_B    
                                                     !   ! 
  RT--LANTHGTTETYTRG--------------------   L   +-----4   +----------------1f4k_B    
                                               !     ! 
  --TT------KATTQTTG----LTRT----KA--FTYT   L --5     +--------------------2p7c_B    
                                               ! 
  ------------KT--RGAT--RGNT------------   L   +--------------------------8smh_F

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updated Sun Aug 3 20:47:31 2025