7vou_C : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF HUMAN FORKHEAD BOX PROTEIN IN COMPLEX WITH DNA 1 (Forkhead box protein L2)
reference	Yoon et al. 'Nucleic 50 8929 2022
source	Homo sapiens
experiment	X-ray (resolution=3.10, R-factor=0.227)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Fork head domain;
multimeric complexes	7vov_AB
redundant complexes	7vov_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7vou_C interface=47,48,50,51,52,54,55,71, kppysyvaliamairesaekrltlsgiyqyiiakfpfyeknkkgwqNSiRHNlSLnecfikvpregggerKgnywtldpacedmfe
interface signature	NSRHNSLK

Estimated binding specificities ?

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# IC=4.755 IC/col=0.792 n_of_columns=6

specificity:

A |  20  23  13   0   1  96
C |   2  13  16   0   6   0
G |  13  54   6   0   0   0
T |  61   6  61  96  89   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----FGTTPTRTAT----LT--------   L       +-----------------------------4hqe_A    
                                       +-2 
  ------------QC--KGSG--RTRGRA   L     ! +-----------------------------3gz6_A    
                                     +-3 
  KGQG------------------------       ! !                           +-8h7a_A    
                                   --4 +---------------------------1 
  --------TCTG--YTRT----------       !                             +-7vpz_N    
                                     ! 
  ----DTRT----RGTT----KT------   L   +-----------------------------2o8k_A

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updated Tue Dec 19 23:05:41 2023