| structure name | STRUCTURE OF SCR/EXD COMPLEX BOUND TO A DNA SEQUENCE DERIVED FROM THE FKH GENE (HOMEOTIC PROTEIN SEX COMBS REDUCED) |
| reference | Aggarwal et al. 'Cell(Cambridge,Mass.)' 131 530 2007 |
| source | DROSOPHILA MELANOGASTER |
| experiment | X-ray (resolution=2.60, R-factor=0.233) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| multimeric complexes | 2r5y_AB 2r5z_AB |
| redundant complexes | 2r5y |
| reference complex | 2r5y_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | HRRIQNMK |
Estimated binding specificities ?
| readout + contact |  |
A | 8 14 75 96 0 96 0 0 C | 0 10 8 0 38 0 0 8 G | 40 14 5 0 0 0 96 78 T | 48 58 8 0 58 0 0 10scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: EXD | ||
| TGATTAAT | PubMed | 2r5z_A(1.38e-03), 2r5y_AB(1.75e-07), 2r5z_AB(2.05e-08) |
| ATCAATCAA | PubMed | 2r5y_AB(1.57e-06), 2r5z_AB(7.87e-04) |
| TTGATTGAT | PubMed | 2r5y_AB(1.57e-06), 2r5z_AB(7.87e-04) |
| TGATNNAT | PubMed | 2r5y_AB(1.78e-05), 2r5z_AB(4.40e-03) |
| TGATTNATGG | PubMed | 2r5y_AB(5.83e-14), 2r5z_AB(1.66e-05) |
Dendrogram of similar interfaces ?
matrix format----RT------------------------VAQTNA------ L +5hod_A +--1 --KGRT------------------------IAQCNAYA--RT L +-------3 +1nk2_P ! ! ----RT------------------------NT--NAIARG-- L +-------4 +--1b72_B ! ! RC--RT------------------------ITQCNAACRG-- L ! ! +6a8r_A +-6 +---------2 --RCRT------------------------NT--NAITRG-- ! ! +5zjt_B +--7 ! ----RA------------------------YAQTNAAARG-- L ! ! +------------------6wig_A ! ! ----------------------------RCVACTNAQA---- L ! +--------------------7xrc_C +---9 --RTRT------------------------IAKGNA------ L ! ! +---------------6m3d_C ! ! +------5 ----RA----------------------RCVTCTNAQTRC-- L +-10 +-8 +---------------1au7_A ! ! ! ----------------------------RTVAITNAMCRG-- L ! ! +----------------------1yrn_A +-11 ! ------NGRGTG------LG----LCRG-------------- ! ! +---------------------------7kz0_A -12 ! RT--RT------------------------VAQTNA------ L ! +-----------------------------1fjl_B ! --------YT--RTTGRG--STATEA--ST------------ L +-----------------------------6xg8_A |
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updated Thu Sep 12 16:30:56 2024