interface graph thumbnail
legend  pdf

structure nameETS1 COOPERATIVE BINDING TO WIDELY SEPARATED SITES ON PROMOTER DNA
(Protein C-ets-1)
referenceBabayeva et al. 'Plos 7 e33698 2012
sourceHomo sapiens
experimentX-ray (resolution=3.00, R-factor=0.230)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes1mdm_AB 2nny_AB 3mfk_AB 3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC 4l0y_AB 4l0z_AB 4l18_AB 4l18_EF
reference complex4l18_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRY

Estimated binding specificities ?

readout + contactlogo
# IC=5.300 IC/col=0.883 n_of_columns=6 specificity:   
A |  67   0   0  96  11   9
C |   9   0   0   0   9   9
G |  11  96  96   0   9  67
T |   9   0   0   0  67  11
scan!

home
updated Mon Dec 18 09:00:13 2023