| structure name | CRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 3) (PROTEIN C-ETS-1) |
| reference | Leukemia 28 2040 2014 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=2.30, R-factor=0.231) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 1mdm_AB 2nny_AB 3mfk_AB 3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC 4l0y_AB 4l0z_AB 4l18_AB 4l18_EF |
| redundant complexes | 1mdm_B
 2nny_A
3mfk_A
3wtt_H
3wtu_C
3wtw_C
3wtx_C
4l0z_B
3wts
3wtv
3wty
4l0y
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | KRRY |
Estimated binding specificities ?
| readout + contact |  |
A | 72 0 0 88 8 24 24 24 24 24 11 C | 8 0 0 8 8 24 24 24 24 24 8 G | 8 96 96 0 8 24 24 24 24 24 8 T | 8 0 0 0 72 24 24 24 24 24 69scan! |
Dendrogram of similar interfaces ?
matrix format--------------KT--RG--RGYA------ L +4l18_B +----------------3 --------------KT--RG--RGYA------ L ! ! +4lg0_B ! +-1 --------------KT--RG--RGYA------ L +--5 +3wts_C ! ! ------------DCKT--RG--RGYA------ L ! ! +1dux_F +---6 +----------------2 ------------ECKT--RGATRGNT------ L ! ! +1pue_E +-7 ! --------------------NTCT--NGST-- L ! ! +-------------------1if1_B +-8 ! ------------------TT--CT--NGKG-- L ! ! +-----------------------7oot_B +-9 ! --RC---------------------------- ! ! +------------------------6l9z_S ! ! NC----------------TT--CT--NGKG-- L +-10 +-------------------------7rh2_B ! ! ------LTNTHG--RTYTPT------------ L ! ! +-------------6qil_A +-11 +-----------4 ----RC-------------------------- ! ! +-------------7cow_T +-12 ! --------------KT--RG--RAYA------ L ! ! +--------------------------6vge_A +-13 ! ------------DCKT--RGSTRGYA------ L ! ! +---------------------------4bnc_A -14 ! ------------DCKT--RGATRCYA------ L ! +---------------------------5e8i_D ! ------------DCKT--RG--RGYA----KA L +---------------------------5jvt_A |
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updated Fri Sep 13 18:27:36 2024