interface graph thumbnail
legend  pdf

structure nameIRF TRANSCRIPTION FACTOR
(Interferon regulatory factor 4)
referenceCasarotto et al. 'Nucleic 49 2255 2021
sourceHomo sapiens
experimentX-ray (resolution=2.95, R-factor=0.186)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInterferon regulatory factor transcription f;
multimeric complexes7jm4_GH 7o56_AB 7ogs_AB 7ogs_EF 7oot_AB 7rh2_GH 8jkl_CD 8jkl_GH 8jkq_DG 8jkq_FH 8jks_CD 8jks_GH
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTRCK

Estimated binding specificities ?

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# IC=4.748 IC/col=0.791 n_of_columns=6 specificity:   
A |   5   6  66  80  81   0
C |   6   5  15   6   5  96
G |   5  80   5   5   5   0
T |  80   5  10   5   5   0
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updated Tue Dec 17 09:19:33 2024