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structure nameX-RAY STRUCTURE OF INTERFERON REGULATORY FACTOR 4 DNA BINDING DOMAIN BOUND TO AN INTERFERON-STIMULATED RESPONSE ELEMENT SOLVED BY PHOSPHORUS AND SULPHUR SAD METHODS
(Interferon regulatory factor 4)
referenceAgnarelli et al. 'Acta 77 202 2021
sourceHomo sapiens
experimentX-ray (resolution=2.60, R-factor=0.214)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInterferon regulatory factor transcription f;
multimeric complexes7jm4_GH 7o56_AB 7ogs_AB 7ogs_EF 7oot_AB 7rh2_GH 8jkl_CD 8jkl_GH 8jkq_DG 8jkq_FH 8jks_CD 8jks_GH
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTRCK

Estimated binding specificities ?

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# IC=4.572 IC/col=0.762 n_of_columns=6 specificity:   
A |   0   5   5  11   0   6
C |   0  15   5   5  85   5
G |  96  11   6  15   6   5
T |   0  65  80  65   5  80
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Dendrogram of similar interfaces ?

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updated Fri Sep 13 05:23:53 2024