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structure nameX-RAY STRUCTURE OF INTERFERON REGULATORY FACTOR 4 DNA BINDING DOMAIN BOUND TO AN INTERFERON-STIMULATED RESPONSE ELEMENT
(Interferon regulatory factor 4)
referenceAgnarelli et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=2.37, R-factor=0.218)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInterferon regulatory factor transcription f;
multimeric complexes7jm4_GH 7o56_AB 7ogs_AB 7ogs_EF 7oot_AB 7rh2_GH 8jkl_CD 8jkl_GH 8jkq_DG 8jkq_FH 8jks_CD 8jks_GH
reference complex7oot_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTRCNK

Estimated binding specificities ?

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# IC=5.300 IC/col=0.883 n_of_columns=6 specificity:   
A |   9   0   0  11   9  96
C |   9   0   0   9  67   0
G |  67   0   0   9   9   0
T |  11  96  96  67  11   0
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updated Fri Sep 13 05:25:37 2024