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legend  pdf

structure nameTRANSCRIPTION FACTOR BARHL2 BOUND TO DNA SEQUENCES
(BarH-like 2 homeobox protein)
referenceMorgunova et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=0.95, R-factor=0.145)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes8pm5_GM 8pn4_GM
redundant complexes8pm5_M 8pm7_A 8pmc_G 8pmn_A 8pmv_J 8pn4_D 8pna_A 8pnc_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRTQNT

Estimated binding specificities ?

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# IC=6.654 IC/col=0.951 n_of_columns=7 specificity:   
A |  10  10   0   0  10  96   0
C |  64  23   0   0   0   0   0
G |  12  53   0   0  10   0  96
T |  10  10  96  96  76   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RT--IAQCNA----MG----   L                          +---1b72_A    
                                         +------------2 
  RART--VTKGNA------KA--   L             !            +---2lkx_A    
                                 +-------4 
  --RTQTVAQTNA----------   L     !       !                 +8osb_E    
                                 !       ! +---------------1 
  ------NCICNARGRG------   L   +-5       +-3               +4xrm_B    
                               ! !         ! 
  --RC--IAQCNA----YC----   L   ! !         +----------------3rkq_B    
                             --6 ! 
  ------VTCCNA----QA--RT   L   ! +------------------------8g87_X    
                               ! 
  ----------------YCFAKC       +-------------------------6pe2_B    
                             

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updated Sat Sep 14 11:44:30 2024