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legend  pdf

structure nameTRANSCRIPTION FACTOR BARHL2 BOUND TO DNA SEQUENCES
(BarH-like 2 homeobox protein)
referenceMorgunova et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=0.95, R-factor=0.145)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes8pm5_GM 8pn4_GM
redundant complexes8pm5_M 8pm7_A 8pmc_G 8pmn_A 8pmv_J 8pn4_D 8pna_A 8pnc_H
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRTQNT

Estimated binding specificities ?

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# IC=6.552 IC/col=0.936 n_of_columns=7 specificity:   
A |  10  10   0   0  10  96   0
C |  64  21   0   0   2   0   0
G |  10  53   0   0  10   0  96
T |  12  12  96  96  74   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RT--IAQCNA----MG----   L       +-----------------------------1b72_A    
                                 +-4 
  RART--VTKGNA------KA--   L     ! +-----------------------------2lkx_A    
                                 ! 
  --RTQTVAQTNA----------   L   +-5                            +8osb_E    
                               ! !            +---------------1 
  ------NCICNARGRG------   L   ! !       +----2               +4xrm_B    
                               ! !       !    ! 
  --RC--IAQCNA----YC----   L --6 +-------3    +----------------3rkq_B    
                               !         ! 
  ------VTCCNA----QA--RT   L   !         +---------------------8g87_X    
                               ! 
  ----------------YCFAKC   L   +-----------------------------6pe2_B    
                             

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updated Wed Dec 18 19:14:49 2024