interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1 (V170A), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
referenceShiina et al. J.Mol.Biol. 427 1655 2015
experimentX-ray (resolution=2.70, R-factor=0.232)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRY

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |  54   0   0  54
C |  16   0   0  13
G |  13  96  96  13
T |  13   0   0  16
scan!

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updated Mon Dec 16 22:35:15 2024