interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1(Y329A), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
referenceShiina et al. J.Mol.Biol. 427 1655 2015
experimentX-ray (resolution=2.80, R-factor=0.237)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRRY

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |  13   0   0  13
C |  13  96  96  13
G |  16   0   0  13
T |  54   0   0  57
scan!

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updated Mon Dec 16 22:35:40 2024