interface graph thumbnail
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structure nameCRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 2)
(PROTEIN C-ETS-1)
referenceLeukemia 28 2040 2014
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.220)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes1mdm_AB 2nny_AB 3mfk_AB 3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC 4l0y_AB 4l0z_AB 4l18_AB 4l18_EF
reference complex4l18_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRY

Estimated binding specificities ?

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# IC=3.520 IC/col=0.880 n_of_columns=4 specificity:   
A |   0   0   0  19
C |  19  96  96  19
G |   1   0   0  20
T |  76   0   0  38
scan!

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updated Thu Sep 12 19:44:50 2024