interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 2)
(PROTEIN C-ETS-1)
referenceLeukemia 28 2040 2014
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.220)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKRRY

Estimated binding specificities ?

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# IC=3.002 IC/col=0.750 n_of_columns=4 specificity:   
A |   6   0   1  17
C |  16  95  95  18
G |  13   0   0  18
T |  61   1   0  43
scan!

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updated Mon Dec 16 23:53:22 2024