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legend  pdf

structure nameCRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
referenceTahirov et al.
experimentX-ray (resolution=3.00, R-factor=0.244)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
multimeric complexes1gtw_AB 1gu4_AB 1gu5_AB 1h88_ABC 1h89_ABC 1h8a_ABC 1hjb_ABC 1hjb_DEF 1io4_ABC 2e42_AB 2e43_AB 6mg1_AB 6mg2_AB 6mg3_AB 7l4v_AB 7upz_AB
reference complex6mg1_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNVSR

Estimated binding specificities ?

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# IC=3.968 IC/col=0.794 n_of_columns=5 specificity:   
A |   9   9  67  96  96
C |  11  11   9   0   0
G |  67  67   9   0   0
T |   9   9  11   0   0
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updated Thu Sep 12 14:43:12 2024