| structure name | A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER (PROTEIN TRANSCRIPTION FACTOR NF-KB P65) |
| reference | Chen et al. Nat.Struct.Biol. 5 67 1998 |
| source | Mus musculus |
| experiment | X-ray (resolution=2.40, R-factor=0.213) |
| structural superfamily | p53-like transcription factors;E set domains; |
| sequence family | Rel homology domain RHD; IPT/TIG domain; |
| multimeric complexes | 1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD |
| redundant complexes | 1le5 2i9t 1ram 1le9 1vkx 1lei |
| reference complex | 9bdw_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: NF-KB P65 | ||
| CAGGAA | PubMed | 1ram_AB(6.34e-03) |
| GGACTCCCC | PubMed | 1le5_AB(3.07e-03), 1le9_AB(4.35e-05), 1vkx_AB(1.42e-03) |
| GGGCCTTTCC | PubMed | 1le5_AB(9.82e-05), 1le5_EF(8.52e-03), 1le9_AB(1.72e-07), ... (total=5) |
Dendrogram of similar interfaces ?
matrix formatRGRGYTCCEC----------------KT-------- L +2v2t_A +-----2 ----YT--------------------RT-------- ! ! +2ram_B ! +-1 RGRGYTCTEC--RT------------RT----KA-- L ! +2o61_A +------5 RGRGYTCTEC----------------RT-------- L ! ! +1gji_A ! ! +-3 RGRGYTCCEC----------------KG--PTKTRG L +----8 +--4 +1nfk_B ! ! ! RGRGYTCCEC------HG--------KG-------- L ! ! +--1a3q_A ! ! RGRG----EG--RG---------------------- L --9 +------------1bvo_A ! ----YT--TTEC--SA-------------------- ! +-----------1imh_D +-----7 RG--YTTCEC------RG----RT--QG-------- L ! +----------1p7h_N +-6 ------------------RGKT--TTQART------ L +----------1a66_A |
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updated Thu Sep 12 16:32:00 2024