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structure nameMOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS
(DNA ENDONUCLEASE I-CREI)
referenceCabaniols et al. Nature 456 107 2008
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=1.95, R-factor=0.150)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1bp7_AB 1bp7_CD 1g9y_AB 1t9i_AB 1t9j_AB 1u0c_AB 1u0d_AB 2i3p_AB 2vbj_AB 2vbo_AB 3mxb_AB 3mxb_RS 4aad_AB 4aae_AB 4aaf_AB 4aag_AB 4aqu_AB 6fb8_AB
reference complex1t9i_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQNSSRKQTYRSSVNKT

Estimated binding specificities ?

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# IC=7.530 IC/col=0.941 n_of_columns=8 specificity:   
A |  59  96  82  96   0   7   0  75
C |   7   0   7   0   0   7  96   7
G |  16   0   0   0  96  66   0   7
T |  14   0   7   0   0  16   0   7
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updated Thu Sep 12 16:34:23 2024