interface graph thumbnail
legend  pdf

structure nameCOOPERATIVE DNA BINDING BY TWO RELA DIMERS
(TRANSCRIPTION FACTOR P65)
referenceGhosh et al. 'J. 292 18821 2017
sourceMUS MUSCULUS
experimentX-ray (resolution=2.50, R-factor=0.221)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD
reference complex9bdw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCERR

Estimated binding specificities ?

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# IC=3.640 IC/col=0.728 n_of_columns=5 specificity:   
A |  20  15   6   0   3
C |  16  10  88  92  88
G |  15   9   2   4   3
T |  45  62   0   0   2
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updated Thu Sep 12 22:01:51 2024