6fb8_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE I-CREI HOMING ENDONUCLEASE D75N VARIANT IN COMPLEX WITH AN ALTERED VERSION OF ITS TARGET DNA AT 5NNN REGION IN THE PRESENCE OF MAGNESIUM (DNA endonuclease I-CreI)
reference	Molina et al. 'Sci 8 10286 2018
source	Chlamydomonas reinhardtii
experiment	X-ray (resolution=2.45, R-factor=0.189)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	1bp7_AB 1bp7_CD 1g9y_AB 1t9i_AB 1t9j_AB 1u0c_AB 1u0d_AB 2i3p_AB 2i3q_AB 4aad_AB 4aae_AB 4aaf_AB 4aag_AB 4aqu_AB 6fb8_AB
reference complex	1t9i_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fb8_A interface=21,23,25,27,29,31,32,37,43,45,67,69,72,74,138,139, ntkynkefllylagfvdgdgSiIaQiKpNqSYkfkhQlsltfQvTqktqrrwfldklvdeigvgyvRdRgsVsNyilseikplhnfltqlqpflklkqkqanlvlkiieqlpsakespdkflevctwvdqiaalndsKTrkttsetvravldaa
interface signature	SIQKNSYQQTRRVNKT

Estimated binding specificities ?

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# IC=13.792 IC/col=1.061 n_of_columns=13

specificity:

A |   4  81   4   0   0  91   4   0   4   0   0   4  96
C |   7   4  84   0  86   0   0   0   9   0   0   4   0
G |   4   4   4  96   6   1  92   0   4   0   0  81   0
T |  81   7   4   0   4   4   0  96  79  96  96   7   0

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updated Fri Jan 9 06:14:13 2026