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structure nameCRYSTAL STRUCTURE OF THE I-CREI HOMING ENDONUCLEASE D75N VARIANT IN COMPLEX WITH AN ALTERED VERSION OF ITS TARGET DNA AT 5NNN REGION IN THE PRESENCE OF MAGNESIUM
(DNA endonuclease I-CreI)
referenceMolina et al. 'Sci 8 10286 2018
sourceChlamydomonas reinhardtii
experimentX-ray (resolution=2.45, R-factor=0.189)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1bp7_AB 1bp7_CD 1g9y_AB 1t9i_AB 1t9j_AB 1u0c_AB 1u0d_AB 2i3p_AB 2vbj_AB 2vbo_AB 3mxb_AB 3mxb_RS 4aad_AB 4aae_AB 4aaf_AB 4aag_AB 4aqu_AB 6fb8_AB
reference complex1t9i_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKNSYQQTRRVNKT

Estimated binding specificities ?

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# IC=13.810 IC/col=1.062 n_of_columns=13 specificity:   
A |   4   4  96  96  82  96   0   4   4   0   0   0  82
C |   4  82   0   0   4   0  91   0   6  96   4   5   4
G |   4   4   0   0   4   0   1   0  86   0  82   0   4
T |  84   6   0   0   6   0   4  92   0   0  10  91   6
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updated Sat Aug 2 11:02:58 2025