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structure nameC-TERMINAL BZIP DOMAIN OF HUMAN C/EBPBETA BOUND TO DNA WITH CONSENSUS RECOGNITION WITH GT MISMATCH
(CCAATenhancer-binding protein beta)
referenceHorton et al. 'Nucleic 49 5084 2021
sourceHomo sapiens
experimentX-ray (resolution=1.75, R-factor=0.200)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
multimeric complexes1gtw_AB 1gu4_AB 1gu5_AB 1h88_ABC 1h89_ABC 1h8a_ABC 1hjb_ABC 1hjb_DEF 1io4_ABC 2e42_AB 2e43_AB 6mg1_AB 6mg2_AB 6mg3_AB 7l4v_AB 7upz_AB 8k8d_AB
reference complex6mg1_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRNAVSR

Estimated binding specificities ?

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# IC=7.660 IC/col=0.958 n_of_columns=8 specificity:   
A |   0   0   0  96  96  10   0  28
C |  96   0  28   0   0  19  96  38
G |   0  96   0   0   0  19   0  11
T |   0   0  68   0   0  48   0  19
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updated Sat Aug 2 16:59:55 2025