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structure nameNF-KAPPAB RELA HOMO-DIMER BOUND TO AT-CENTRIC KAPPAB DNA
(Transcription factor p65)
referenceBiswas et al. Proc.Natl.Acad.Sci.USA 121 e2405555121 2024
sourceMus musculus
experimentX-ray (resolution=2.03, R-factor=0.226)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD 9bdu_AB 9bdv_AB 9bdw_AB 9bdx_AB
reference complex9bdw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCERRK

Estimated binding specificities ?

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# IC=5.710 IC/col=0.952 n_of_columns=6 specificity:   
A |   0   0   0   0  96  54
C |  13   0   0   0   0  16
G |  15  96  82  96   0  13
T |  68   0  14   0   0  13
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updated Tue Dec 17 21:41:20 2024