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structure nameNF-KAPPAB RELA HOMO-DIMER BOUND TO TA-CENTRIC KAPPAB DNA
(Transcription factor p65)
referenceTsodikov et al. Proc.Natl.Acad.Sci.USA 121 e2405555121 2024
sourceMus musculus
experimentX-ray (resolution=1.90, R-factor=0.193)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD
reference complex9bdw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCERR

Estimated binding specificities ?

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# IC=4.465 IC/col=0.638 n_of_columns=7 specificity:   
A |  12  12   2   0   2  64  39
C |  56  12   3   0   2   4  18
G |  16  12  88  96  90  23  18
T |  12  60   3   0   2   5  21
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updated Fri Sep 13 15:13:29 2024