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structure nameNF-KAPPAB RELA HOMO-DIMER BOUND TO CG-CENTRIC KAPPAB DNA
(Transcription factor p65)
referenceTsodikov et al. Proc.Natl.Acad.Sci.USA 121 e2405555121 2024
sourceMus musculus
experimentX-ray (resolution=3.60, R-factor=0.324)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1le5_AB 1le5_EF 1le9_AB 1le9_EF 1lei_AB 1ram_AB 1vkx_AB 2i9t_AB 2ram_AB 3gut_ABD 3gut_CF 3gut_EGH 5u01_ABCD 9bdu_AB 9bdv_AB 9bdw_AB 9bdx_AB
reference complex9bdw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCERR

Estimated binding specificities ?

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# IC=6.383 IC/col=0.491 n_of_columns=13 specificity:   
A |   7   0   0   0  75  75  24  24  24  24  24  24   7
C |   7   0   0   0   7   7  24  24  24  24  24  24   7
G |   9  96  96  96   7   7  24  24  24  24  24  24  75
T |  73   0   0   0   7   7  24  24  24  24  24  24   7
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updated Sun Aug 3 05:07:50 2025