structure name | GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN IN COMPLEX WITH METHYLATED PRECURSOR FOR A MODERN RECOGNITION ELEMENT (METHYLATED PRE-GBS) (Glucocorticoid receptor) |
reference | Ortlund et al. 'Nucleic 49 8923 2021 |
source | Homo sapiens |
experiment | X-ray (resolution=2.00, R-factor=0.183) |
structural superfamily | Glucocorticoid receptor-like DNA-binding domain; |
sequence family | Zinc finger, C4 type two domains; |
multimeric complexes | 1glu_AB 5va0_AB 5va7_AB 6x6d_AB 6x6e_AB |
redundant complexes | 6x6d_B 5va0_B 5va7_B 6bqu_A 1glu_A |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | KVR |
Estimated binding specificities ?
contact |
A | 0 0 24 13 16 C | 0 0 24 54 13 G | 96 0 24 16 13 T | 0 96 24 13 54scan! |
Dendrogram of similar interfaces ?
matrix formatECKG--KGRG +-----------------------------3dzy_A ! DAKG--RGRG L ! +---------------------4iqr_B ! +---10 ECKGAGKGRG L ! ! +---------------------1hcq_E -14 ! DGKG--RTRG L ! ! +3cbb_A ! ! +----------1 ECKG--KGRG L ! ! ! +2ff0_A ! ! ! ECKG--RGRG L +-13 +-------------7 +---2nll_B ! ! ! +-----5 --KGVT--RG ! ! ! ! +---5emp_A ! ! +-6 --KAVA--RA L ! ! ! +5e69_A ! ! +--------3 ECKG--RGRG L ! ! +3dzy_D +-12 --KGVT--RG L ! +6x6e_A ! +-------------2 ECKG--RGRG L ! +----8 +5uan_B ! ! ! ECKG--KGRG ! +---9 +--------------4nqa_H ! ! ! ECKG--RGRG L ! ! ! +-1dsz_A +-11 +-----------------4 ETKGAT--RG L ! +-1lat_A ! --KGVG--RG L +-----------------------4tnt_B |
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updated Fri Dec 23 02:14:06 2022