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structure nameGLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN IN COMPLEX WITH UNMODIFIED PRECURSOR FOR A MODERN RECOGNITION ELEMENT (PRE-GBS)
(Glucocorticoid receptor)
referenceOrtlund et al. 'Nucleic 49 8923 2021
sourceHomo sapiens
experimentX-ray (resolution=2.48, R-factor=0.191)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1glu_AB 1r4o_AB 1r4r_AB 3fyl_AB 3g6p_AB 3g6q_AB 3g6r_AB 3g6t_AB 3g6u_AB 3g8u_AB 3g8x_AB 3g97_AB 3g99_AB 3g9i_AB 3g9j_AB 3g9m_AB 3g9o_AB 3g9p_AB 4hn5_AB 4hn6_AB 5cbx_AB 5cbx_EF 5cby_AB 5cc1_AB 5cc1_WX 5e69_AB 5e6a_AB 5e6b_AB 5e6c_AB 5va0_AB 5va7_AB 6bse_AB 6x6d_AB 6x6e_AB
reference complex3g9m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=3.968 IC/col=0.661 n_of_columns=6 specificity:   
A |  67  11  24  67   0   0
C |  11   9  24   9  96   0
G |   9  67  24  11   0  96
T |   9   9  24   9   0   0
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updated Sun Jun 28 20:53:50 2026