structure nameHUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE
(GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyRap30/74 interaction domains;"Winged helix" DNA-binding domain;
sequence familyTranscription initiation factor IIF, beta;
multimeric complexes5iy6_AMPTV 5iy7_ABEMNPTV 5iy8_ABEMNPTV 5iy9_ABEMNPTV 5iya_AMPT 5iyb_ABEMNPT 5iyc_ABEMNPT 5iyd_ABEMNPT 6o9l_7AMNPT 6o9l_ES 7lbm_AMOPTW 7lbm_BEQ 7nvr_7AEMORU 7nvs_AMORU 7nvs_BE 7nvt_AMORU 7nvu_ABEMORU 7nvy_7AMORU 7nvy_BE 7nvz_7AMORU 7nw0_7ABEMORU 7zwd_AMORUbc 7zwd_BE 7zx7_AMORUbc 7zx7_BE
redundant complexes5iy6 5iy9 6o9l 5iya 5iy7 5iyb 5iy8 5iyd
reference complex5iy6_T
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKIH

Estimated binding specificities ?

contactlogo
# IC=2.674 IC/col=0.535 n_of_columns=5 specificity:   
A |  11   0   9  24   9
C |   9   0  67  24   9
G |  67  96   9  24   9
T |   9   0  11  24  69
scan!

Dendrogram of similar interfaces ?

matrix format
  
  KG----------------------ITHG   L                     +--------------5iyc_T    
                                               +-------5 
  --------------AT------------                 !       +--------------5fyw_R    
                                               ! 
  --------------------YG------                 !                      +2heo_D    
                                         +-----7          +-----------1 
  --------------------RCKT----           !     !          !           +2acj_B    
                                         !     !   +------4 
  --------------------RG------           !     !   !      !          +-1qbj_C    
                                         !     !   !      !        +-2 
  --------------RGRG----------   L     +-8     +---6      +--------3 +-1cf7_A    
                                       ! !         !               ! 
  ----ETNT--SCRGHC------------   L     ! !         !               +--4h0e_A    
                                       ! !         ! 
  ------SGQG--YCNC------------       +-9 !         +------------------2ve9_C    
                                     ! ! ! 
  --MG------TGQAAT--SARG------   L   ! ! +----------------------------2p5l_D    
                                   -10 ! 
  ----FG----TTPTRTAT--LT------   L   ! +----------------------------4hqe_A    
                                     !  
  ----------STQASGATSTQT--QA--   L   +----------------------------4on0_B    
                                   

home
updated Thu Sep 12 21:33:58 2024