interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF ASPA-DNA COMPLEX: NOVEL CENTROMERE BINDNG PROTEIN- CENTROMERE COMPLEX
(ASPA)
referenceScience 349 1120 2015 X-RAY DIFFRACTION
sourceSULFOLOBUS SP. NOB8H2
experimentX-ray (resolution=2.65, R-factor=0.262)
structural superfamily"Winged helix" DNA-binding domain;
multimeric complexes5k1y_ABCDEF 5k5o_ABCD 5k5q_ABCDEF 5k5r_ABCDEF 5kk1_ABCDEF
redundant complexes5k1y_E 5k5o_B 5k5r_E 5kk1_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYQTQ

Estimated binding specificities ?

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# IC=7.099 IC/col=1.014 n_of_columns=7 specificity:   
A |   0  96   0  13  96   0  54
C |   0   0   0  54   0   0  16
G |  96   0  96  16   0   0  13
T |   0   0   0  13   0  96  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------RGSTRTSTHG----------------RA----   L                                       +3zpl_B    
                                                         +---------------------------1 
  ------DCLT--AGTTRG------RG--------RA----   L           !                           +5h3r_A    
                                                         ! 
  ----------------NAST--HT--STLT----------   L         +-5                    +------7cby_C    
                                                       ! !                  +-2 
  --------------NAST--RTHT--ST------------   L         ! !    +-------------3 +------3l2c_A    
                                                       ! !    !             ! 
  ----LANTHGTTETYTRG----------------------   L       +-6 +----4             +--------1f4k_B    
                                                     ! !      ! 
  --TT------KATTQTTG----LTRT----KA----FTYT   L       ! !      +----------------------2p7c_B    
                                                   +-7 ! 
  ------SG--PTPGTT----------------HG------   L     ! ! +-----------------------------7d98_Q    
                                                 +-8 ! 
  ----------------------YG----------------       ! ! +-----------------------------3eyi_B    
                                               --9 ! 
  RC----EGRTRGRGYT------------------------   L   ! +-----------------------------4yo2_A    
                                                 ! 
  ----------NCTTNA------VTNT--------------   L   +-----------------------------1pp7_U    
                                               

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updated Fri Sep 13 19:57:56 2024