interface graph thumbnail
legend  pdf

structure nameSTREPTOMYCES COELICOLOR ZINC UPTAKE REGULATOR COMPLEXED WITH ZINC AND DNA (TRIMER OF DIMERS)
experimentNMR
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFerric uptake regulator family;
multimeric complexes7vo0_GHKLMN 7vo9_GHMN 7vpz_CDFMN 7x74_CDFGHMN 7x75_CDFGHKLMN 7x76_CDFGHMN
redundant complexes7vo9_N 7x76_H 7vpz 7x74 7x75
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQLTTYR

Estimated binding specificities ?

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# IC=6.080 IC/col=0.676 n_of_columns=9 specificity:   
A |   0   6   6  24   0  78  24   6   6
C |   0   6   6  24  96   6  24   6   6
G |   0   6  78  24   0   6  24  78   6
T |  96  78   6  24   0   6  24   6  78
scan!

Dendrogram of similar interfaces ?

matrix format
  
  TT------KATTQTTG----LTRT----KAFTYT   L           +-----------------------------2p7c_B    
                                                 +-2 
  --------------------YG------------           +-3 +-----------------------------3eyi_B    
                                               ! ! 
  ------------NAST--RTHT--ST--------   L     +-4 +-----------------------------3l2c_A    
                                             ! ! 
  --------------NAST--HT--STLT------   L   +-5 +-----------------------------7cby_C    
                                           ! ! 
  --VTSARGTA--RT--------------------   L --6 +-----------------------------6za3_B    
                                           ! 
  ------------QTVA----QTNA----------   L   !                             +8osb_E    
                                           +-----------------------------1 
  --------------VT----KGNA----KA----   L                                 +2lkx_A    
                                         

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updated Wed Dec 18 13:34:46 2024