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structure nameRNA POLYMERASE II CORE PRE-INITIATION COMPLEX WITH OPEN PROMOTER DNA
(TATA-BOX-BINDING PROTEIN)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyTATA-box binding protein-like;
sequence familyTranscription factor TFIID or TATAbinding;
multimeric complexes5iy6_AMPTV 5iy7_ABEMNPTV 5iy8_ABEMNPTV 5iy9_ABEMNPTV 5iya_AMPT 5iyb_ABEMNPT 5iyc_ABEMNPT 5iyd_ABEMNPT 6mzm_ABTW 6o9l_7AMNPT 6o9l_ES 7lbm_AMOPTW 7lbm_BEQ 7nvr_7AEMORU 7nvs_AMORU 7nvs_BE 7nvt_AMORU 7nvu_ABEMORU 7nvy_7AMORU 7nvy_BE 7nvz_7AMORU 7nw0_7ABEMORU 7zwd_AMORUbc 7zwd_BE 7zx7_AMORUbc 7zx7_BE 8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ 8iue_34BEPUVW 8iuh_1I 8iuh_OQ
redundant complexes6o9l 6mzm 7nvr 5iy6 7nvs 5iy8 7nvt 5iy9 5iya 5iyb 5iyc 5iyd 7nvy 7nvz 7nw0 7egd 7egj 5iy7 5fur 7edx 7eg7 7eg8 7eg9 7ega
reference complex5iy6_P
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVFLFVTNVFPLFVT

Estimated binding specificities ?

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# IC=8.431 IC/col=1.054 n_of_columns=8 specificity:   
A |   0  96  13  96  96  54  96   0
C |   0   0  13   0   0  13   0   0
G |   0   0  16   0   0  13   0  96
T |  96   0  54   0   0  16   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  NTVTFT--LTFAVATT--NAVTFAPALTFTVATA--   L                              +7nvu_O    
                                                               +--------1 
  NTVAFA--LAFT--TCQANTVAFAPALAFTVTTT--   L                     !        +6cnb_R    
                                                           +---4 
  NTVTFT--LTFAVATT--NAVTFTPALTFAVATA--   L                 !   !       +1qna_B    
                                                           !   +-------3 
  NTVAFC--LTFAVATT--NAVTFTPALTFTVATA--   L   +-------------5           ! +4wzs_D    
                                             !             !           +-2 
  NTVTFA--LAFTVATT--NAVTFTPALTFAVTTA--   L   !             !             +4roc_B    
                                           --6             ! 
  NAVAFTPALTFAVATA----VAFTPALTFAVAST--   L   !             +------------1ais_A    
                                             ! 
  ----------------------------------RT       +--------------------------6mup_M    
                                           

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updated Fri Sep 13 05:01:48 2024