7nvu_O : 3D-footprint complex

structure name	RNA POLYMERASE II CORE PRE-INITIATION COMPLEX WITH OPEN PROMOTER DNA (TATA-BOX-BINDING PROTEIN)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	TATA-box binding protein-like;
sequence family	Transcription factor TFIID or TATAbinding;
redundant complexes	6o9l 6mzm 7nvr 5iy6 7nvs 5iy8 7nvt 5iy9 5iya 5iyb 5iyc 5iyd 7nvy 7nvz 7nw0 7egd 7egj 5iy7 5fur 7edx 7eg7 7eg8 7eg9 7ega
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7nvu_O interface=9,11,39,54,56,62,64,99,101,130,131,145,147,153,155, sgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkgfrk
interface signature	NVFLFVTNVFPLFVT

Estimated binding specificities ?

contact

# IC=8.431 IC/col=1.054 n_of_columns=8

specificity:

A |   0  96  13  96  96  54  96   0
C |   0   0  13   0   0  13   0   0
G |   0   0  16   0   0  16   0  96
T |  96   0  54   0   0  13   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  NTVTFT--LTFAVATT--NAVTFAPALTFTVATA--   L                              +7nvu_O    
                                                               +--------1 
  NTVAFA--LAFT--TCQANTVAFAPALAFTVTTT--   L                     !        +6cnb_R    
                                                           +---4 
  NTVTFT--LTFAVATT--NAVTFTPALTFAVATA--   L                 !   !       +1qna_B    
                                                           !   +-------3 
  NTVAFC--LTFAVATT--NAVTFTPALTFTVATA--   L   +-------------5           ! +4wzs_D    
                                             !             !           +-2 
  NTVTFA--LAFTVATT--NAVTFTPALTFAVTTA--   L   !             !             +4roc_B    
                                           --6             ! 
  NAVAFTPALTFAVATA----VAFTPALTFAVAST--   L   !             +------------1ais_A    
                                             ! 
  ----------------------------------RT       +--------------------------6mup_M

home
updated Tue Dec 17 10:19:32 2024