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structure nameCRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN RAMP2 RESPONSE ELEMENT
(RETINOIC ACID RECEPTOR RXR-ALPHA)
referencePoussin-Courmontagne et al. Sci.Rep. 5 8216 2015
sourceHOMO SAPIENS
experimentX-ray (resolution=2.07, R-factor=0.167)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1by4_BC 1dsz_AB 1r0n_AB 1ynw_AB 2nll_AB 4cn2_CD 4cn3_AD 4cn3_BC 4cn5_AB 4cn7_AB 4cn7_EF 6fbq_AB 6fbr_AB 6xwg_CD 6xwh_CD 8hbm_AB 8hbm_EF
reference complex6fbq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKKRR

Estimated binding specificities ?

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# IC=6.671 IC/col=0.556 n_of_columns=12 specificity:   
A |  11  24  24  24  24  24   8   0   0   0   0  80
C |   8  24  24  24  24  24  10   0   0   8  96   0
G |  69  24  24  24  24  24  61  96  96   0   0   8
T |   8  24  24  24  24  24  17   0   0  88   0   8
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updated Thu Sep 12 18:57:02 2024