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structure nameCRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO AN IDEALIZED DR1 RESPONSE ELEMENT
(RETINOIC ACID RECEPTOR RXR-ALPHA)
referencePoussin-Courmontagne et al. Sci.Rep. 5 8216 2015
sourceHOMO SAPIENS
experimentX-ray (resolution=2.34, R-factor=0.175)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1by4_BC 1dsz_AB 1r0n_AB 1ynw_AB 2nll_AB 4cn2_CD 4cn3_AD 4cn3_BC 4cn5_AB 4cn7_AB 4cn7_EF 6fbq_AB 6fbr_AB 6xwg_CD 6xwh_CD
reference complex6fbq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureEKKR

Estimated binding specificities ?

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# IC=5.417 IC/col=0.903 n_of_columns=6 specificity:   
A |  10   0  64   0   0  10
C |   0   0  10  96  96  21
G |  10  96  21   0   0  12
T |  76   0   1   0   0  53
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updated Mon Dec 18 09:55:54 2023