interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA-BINDING DOMAIN BOUND TO THE HUMAN MEP DR1 RESPONSE ELEMENT, PH 4.2
(Retinoic acid receptor RXR-alpha)
referencePoussin-Courmontagne et al. 'Mol. 481 44 2019
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=0.181)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureMEKKRR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  13   0  54  96   0
C |  13   0  13   0  96
G |  16  96  16   0   0
T |  54   0  13   0   0
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updated Tue Dec 17 04:02:40 2024