3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN H-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes7unc_ABabcdefgh 7und_ABEZabdefgh 8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes7unc 7und 8a3y 8bvw 8byq 8bz1 8gxq 8rbx
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ----------RG------------             +-----------------------------7ccr_H    
                                       !  
  --------------IT--------             !                      +------3wkj_D    
                                       !                  +---7 
  ------------------RA--RA             !                  !   !      +6a5l_g    
                                       !                  !   +------2 
  ------------------RG----             !             +----8          +8upf_G    
                                    +-14             !    ! 
  ----------RG------------          !  !             !    !          +3x1t_H    
                                    !  !     +------11    +----------3 
  ------------------RC----          !  !     !       !               +7yqk_C    
                                    !  !     !       !  
  --------------------KG--          !  !     !       !               +7nkx_f    
                                    !  !     !       +---------------1 
  ------------------RA----          !  !     !                       +7e9c_F    
                                    !  +----13  
  ------------------RT----          !        !                       +7kbd_C    
                                    !        !   +-------------------4 
  ----------------HGRG----       +-15        !   !                   +8rbx_V    
                                 !  !        !   !  
  ------------------RT----       !  !        +--12                     +7zs9_e    
                                 !  !            !      +--------------5 
  ------------------RT----       !  !            !    +-9              +6px1_A    
                                 !  !            !    ! ! 
  ------------LA----RG----       !  !            +---10 +--------------7unc_a    
                               -16  !                 !  
  ------------------RG----       !  !                 !              +7ccr_A    
                                 !  !                 +--------------6 
  ------------------RC----       !  !                                +7ux9_E    
                                 !  !  
  NTATATSTRG--------------   L   !  +-----------------------------1dh3_C    
                                 !  
  ------------------RG----       +-----------------------------7y7i_E    
                               

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updated Sun Jan 11 00:04:19 2026