3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN H-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes7unc_ABabcdefgh 7und_ABEZabdefgh 8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes7unc 7und 8a3y 8bvw 8byq 8bz1 8gxq 8rbx
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ------------------RA----          +-----------------------------6g0l_D    
                                    !  
  --------------IT--------          !               +------------------3wkj_D    
                                    !               !  
  ----------RG------------          !               !  +-----------------3x1t_H    
                                    !               !  !  
  ----------RT------------          !        +-----18  !               +-----6nj9_H    
                                    !        !      !  !         +-----8 
  ----------------RA----RA          !        !      !  !         !     +-----6a5l_g    
                                    !        !      !  !     +---9 
  --------------------KG--          !        !      +-17     !   !          +7nkx_f    
                                    !        !         !     !   +----------6 
  ----------------RA------          !        !         !  +-13              ! +1zla_C    
                                    !        !         !  !  !              +-4 
  ----------------RG------          !        !         !  !  !                +8ox0_C    
                                    !        !         !  !  !  
  ----------RG------------          !        !         +-15  +---------------7tn2_D    
                                    !        !            !  
  ----------------RC------          !        !            !                 +7on1_c    
                                    !        !            !  +--------------1 
  ----------------RG------       +-24        !            !  !              +5x0y_G    
                                 !  !        !            +-12  
  ----------------RG------       !  !        !               !              +3w99_F    
                                 !  !        !               +--------------2 
  ----------------RG------       !  !     +-21                              +8jla_C    
                                 !  !     !  !  
  ----------------RC------       !  !     !  !                             +--7xyf_B    
                                 !  !     !  !                   +---------7 
  ----------------RT------       !  !     !  !                   !         +--7kbd_C    
                                 !  !     !  !                +-10  
  ----------------RG------       !  !     !  !                !  !            +7ccr_A    
                                 !  !     !  !                !  +------------5 
  ----------------RT------       !  !     !  !             +-11               +8hr1_E    
                                 !  !     !  !             !  !  
  ----------------RT------       !  !     !  !             !  !             +7zs9_e    
                               -25  !  +-22  !          +-14  +-------------3 
  ----------------RT------       !  !  !  !  !          !  !                +8grq_A    
                                 !  !  !  !  !     +---16  !  
  ------------LA--RG------       !  !  !  !  !     !    !  +---------------7unc_a    
                                 !  !  !  !  !  +-19    !  
  ----------------RG------       !  !  !  !  !  !  !    +-----------------6iy2_A    
                                 !  +-23  !  +-20  !  
  ----------------RC------       !     !  !     !  +----------------------3kwq_E    
                                 !     !  !     !  
  ----------------RC------       !     !  !     +-----------------------4xzq_E    
                                 !     !  !  
  ----------------RT------       !     !  +---------------------------5z23_C    
                                 !     !  
  ----------------RG------       !     +----------------------------7y7i_E    
                                 !  
  NTATATSTRG--------------   L   +-----------------------------1dh3_C    
                               

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updated Mon Aug 4 00:58:05 2025