3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN H-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes8bvw 8byq 8gxq
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  --------------IT----                         +-----------------------------3wkj_D    
                                            +-11  
  ----------RG--------                   +-12  +-----------------------------3x1t_H    
                                         !  !  
  ----------RT--------                +-13  +-----------------------------6nj9_H    
                                      !  !  
  ----------RG--------                !  +-----------------------------7tn2_D    
                                      !  
  ------------------KG                !                           +---7nkx_f    
                                      !           +---------------2 
  ------------LA--RG--                !  +--------4               +---7unc_a    
                                   +-14  !        ! 
  ----------------RC--             !  !  !        +-------------------7on1_c    
                                   !  !  !  
  ----------------RC--             !  !  !                            +--7xyf_B    
                                   !  !  !              +-------------1 
  ----------------RT--             !  !  !          +---3             +--7kbd_C    
                                   !  !  !          !   ! 
  ----------------RG--             !  +-10       +--5   +----------------6iy2_A    
                                   !     !       !  ! 
  ----------------RC--          +-15     !     +-6  +--------------------3kwq_E    
                                !  !     !     ! ! 
  ----------------RG--          !  !     !   +-7 +-----------------------7ccr_A    
                                !  !     !   ! ! 
  ----------------RC--          !  !     ! +-8 +------------------------4xzq_E    
                                !  !     ! ! ! 
  ----------------RT--       +-16  !     +-9 +-------------------------7zs9_e    
                             !  !  !       ! 
  ----------------RG--       !  !  !       +--------------------------7y7i_E    
                             !  !  !  
  ----------------RG--     -17  !  +-----------------------------3w99_F    
                             !  !  
  ----------------RT--       !  +-----------------------------5z23_C    
                             !  
  NTATATSTRG----------   L   +-----------------------------1dh3_C    
                           

home
updated Sat Sep 14 10:42:10 2024