3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN H-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes8bvw 8byq 8gxq
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ------------------RA----                         +-----------------------------6g0l_D    
                                                +-19  
  ----------RG------------                   +-20  +-----------------------------3x1t_H    
                                             !  !  
  --------------IT--------                +-21  +-----------------------------3wkj_D    
                                          !  !  
  ----------RT------------                !  +-----------------------------6nj9_H    
                                          !  
  ----------RG------------                !                                  +----7tn2_D    
                                          !                        +---------7 
  ----------------RG------                !                        !         +----5x0y_G    
                                          !                        !  
  --------------------KG--                !               +-------12             +7nkx_f    
                                          !               !        !  +----------5 
  ----------------RG------                !               !        !  !          +8jla_C    
                                          !               !        !  ! 
  ----------------RC------                !               !        +--9             +7on1_c    
                                          !               !           !           +-1 
  ----------------RA------                !               !           ! +---------3 +1zla_C    
                                          !               !           ! !         ! 
  ----------------RG------                !               !           +-8         +8ox0_C    
                                          !               !             ! 
  ----------------RA----RA             +-22           +--14             +---------6a5l_g    
                                       !  !           !   !  
  ----------------RC------             !  !           !   !                       +--7xyf_B    
                                       !  !           !   !             +---------6 
  ----------------RT------             !  !           !   !             !         +--7kbd_C    
                                       !  !           !   !          +-10  
  ------------LA--RG------             !  !           !   !          !  !            +7unc_a    
                                       !  !           !   !          !  +------------2 
  ----------------RT------             !  !        +-15   !       +-11               +8grq_A    
                                       !  !        !  !   !       !  !  
  ----------------RG------             !  !        !  !   !       !  !             +7ccr_A    
                                       !  !        !  !   +------13  +-------------4 
  ----------------RT------          +-23  !        !  !           !                +8hr1_E    
                                    !  !  !     +-16  !           !  
  ----------------RT------          !  !  !     !  !  !           +---------------7zs9_e    
                                    !  !  !     !  !  !  
  ----------------RG------          !  !  !  +-17  !  +---------------------------6iy2_A    
                                    !  !  !  !  !  !  
  ----------------RC------          !  !  !  !  !  +---------------------------3kwq_E    
                                 +-24  !  +-18  !  
  ----------------RC------       !  !  !     !  +----------------------------4xzq_E    
                                 !  !  !     !  
  ----------------RG------       !  !  !     +----------------------------7y7i_E    
                               -25  !  !  
  ----------------RG------       !  !  +-----------------------------3w99_F    
                                 !  !  
  ----------------RT------       !  +-----------------------------5z23_C    
                                 !  
  NTATATSTRG--------------   L   +-----------------------------1dh3_C    
                               

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updated Wed Dec 18 18:07:11 2024