3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN MH-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes8bvw 8byq 8gxs
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ----------RG----------                            +-----------------------------3x1t_H    
                                                 +-11  
  --------------IT------                      +-12  +-----------------------------3wkj_D    
                                              !  !  
  ----------RT----------                   +-13  +-----------------------------6nj9_H    
                                           !  !  
  ----------RG----------                   !  +-----------------------------7tn2_D    
                                           !  
  --------------------KG                   !                           +---7nkx_f    
                                           !           +---------------2 
  ------------LA--RG----                   !  +--------4               +---7unc_a    
                                        +-14  !        ! 
  ----------------RC----                !  !  !        +-------------------7on1_c    
                                        !  !  !  
  ----------------RC----                !  !  !                            +--7xyf_B    
                                        !  !  !              +-------------1 
  ----------------RT----                !  !  !          +---3             +--7kbd_C    
                                        !  !  !          !   ! 
  ----------------RG----                !  +-10       +--5   +----------------6iy2_A    
                                        !     !       !  ! 
  ----------------RC----             +-15     !     +-6  +--------------------3kwq_E    
                                     !  !     !     ! ! 
  ----------------RC----             !  !     !   +-7 +-----------------------4xzq_E    
                                     !  !     !   ! ! 
  ----------------RG----             !  !     ! +-8 +------------------------7ccr_A    
                                     !  !     ! ! ! 
  ----------------RT----          +-16  !     +-9 +-------------------------7zs9_e    
                                  !  !  !       ! 
  ----------------RG----          !  !  !       +--------------------------7y7i_E    
                                  !  !  !  
  ----------------RG----       +-17  !  +-----------------------------3w99_F    
                               !  !  !  
  ----------------RT----       !  !  +-----------------------------5z23_C    
                             -18  !  
  NTATATSTRG------------   L   !  +-----------------------------1dh3_C    
                               !  
  ------------------RG--       +-----------------------------7n8n_A    
                             

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updated Sat Sep 14 10:32:19 2024