3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN MH-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes8bvw 8byq 8gxs
links to other resourcesNAKB PDBSum PDIdb DNAproDB
  
  ------------------RA----                            +-----------------------------6g0l_D    
                                                   +-19  
  ----------RG------------                      +-20  +-----------------------------3x1t_H    
                                                !  !  
  --------------IT--------                   +-21  +-----------------------------3wkj_D    
                                             !  !  
  ----------RT------------                   !  +-----------------------------6nj9_H    
                                             !  
  ----------RG------------                   !                                  +-----7tn2_D    
                                             !                          +-------7 
  ----------------RA----RA                   !                          !       +-----6a5l_g    
                                             !                          !  
  --------------------KG--                   !                       +-10            +7nkx_f    
                                             !                       !  !     +------5 
  ----------------RG------                   !                       !  !     !      +8jla_C    
                                             !                       !  +-----8 
  ----------------RA------                   !               +------12        !       +1zla_C    
                                             !               !       !        +-------3 
  ----------------RG------                   !               !       !                +8ox0_C    
                                             !               !       !  
  ----------------RC------                   !               !       !               +7on1_c    
                                             !               !       +---------------1 
  ----------------RG------                +-22               !                       +5x0y_G    
                                          !  !               !  
  ----------------RC------                !  !           +--14                      +--7xyf_B    
                                          !  !           !   !            +---------6 
  ----------------RT------                !  !           !   !            !         +--7kbd_C    
                                          !  !           !   !          +-9 
  ------------LA--RG------                !  !           !   !          ! !            +7unc_a    
                                          !  !           !   !          ! +------------2 
  ----------------RT------                !  !           !   !       +-11              +8grq_A    
                                          !  !        +-15   !       !  !  
  ----------------RG------                !  !        !  !   !       !  !             +7ccr_A    
                                          !  !        !  !   +------13  +-------------4 
  ----------------RT------             +-23  !        !  !           !                +8hr1_E    
                                       !  !  !     +-16  !           !  
  ----------------RT------             !  !  !     !  !  !           +---------------7zs9_e    
                                       !  !  !     !  !  !  
  ----------------RG------             !  !  !  +-17  !  +---------------------------6iy2_A    
                                       !  !  !  !  !  !  
  ----------------RC------             !  !  !  !  !  +---------------------------3kwq_E    
                                    +-24  !  +-18  !  
  ----------------RC------          !  !  !     !  +----------------------------4xzq_E    
                                    !  !  !     !  
  ----------------RG------          !  !  !     +----------------------------7y7i_E    
                                 +-25  !  !  
  ----------------RG------       !  !  !  +-----------------------------3w99_F    
                                 !  !  !  
  ----------------RT------     -26  !  +-----------------------------5z23_C    
                                 !  !  
  NTATATSTRG--------------   L   !  +-----------------------------1dh3_C    
                                 !  
  ------------------RG----       +-----------------------------7n8n_A    
                               

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updated Wed Dec 18 17:53:01 2024