3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure namePIC-MEDIATOR IN COMPLEX WITH +1 NUCLEOSOME (T40N) IN MH-BINDING STATE
experimentNMR
structural superfamilyHistone-fold;HRDC-like;RING/U-box;
sequence familyCDKactivating kinase assembly factor MA; RNA polymerase Rpb4; Transcription initiation factor TFIID co; Core histone H2A/H2B/H3/H4; Zinc finger, C3HC4 type RING finger;
multimeric complexes8gxq_ABCDEFGHPQs 8gxs_ABCDEFGHPQ
redundant complexes8bvw 8byq 8gxs
links to other resourcesNAKB PDBSum PDIdb DNAproDB 
  
  RG----       +-----------------------7k6p_D    
               ! 
  ----RC       !                     +--6qld_f    
               !               +-----2 
  ----RC       !               !     +--3kwq_E    
               !        +------3 
  ----RA     --8        !      !        +7xsx_a    
               !     +--4      +--------1 
  ----RG       !     !  !               +7uv9_E    
               !   +-5  ! 
  ----RA   L   !   ! !  +---------------8he5_a    
               ! +-6 ! 
  --LARG       ! ! ! +------------------7unc_a    
               +-7 ! 
  ----RT         ! +--------------------8cww_A    
                 ! 
  ----RT         +---------------------8siy_G

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updated Wed Dec 20 03:07:36 2023