| structure name | STRUCTURE OF A TERNARY FOXO1-ETS1 DNA COMPLEX (PROTEIN C-ETS-1) |
| reference | Geiger et al. 'To ? ? ? |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=2.19, R-factor=0.197) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 1mdm_AB 2nny_AB 3mfk_AB 3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC 3wu1_AB 4l0y_AB 4l0z_AB 4l18_AB 4l18_EF 4lg0_AB |
| redundant complexes |  1k79_D
1k7a_A
1mdm_B
2nny_A
3mfk_A
3wtt_H
3wtu_C
3wtw_C
3wtx_C
3wu1_B
4l0y_B
4l0z_B
5zmc_B
3wts
3wtv
3wty
4l18
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKRRY |
Estimated binding specificities ?
| contact |  |
A | 8 8 1 0 0 8 C | 8 8 0 96 96 11 G | 11 8 8 0 0 8 T | 69 72 87 0 0 69scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ETS-1 | ||
| AGGAAGT | PubMed | 4lg0_B(6.54e-06), 3wu1_AB(5.07e-05), 4lg0_AB(1.06e-03), ... (total=4) |
| TTTTTAT | PubMed | 4lg0_AB(5.39e-03) |
| GAGGAATG | PubMed | 4lg0_B(1.83e-05), 4lg0_AB(4.39e-03), 5zmc_B(6.36e-03) |
| GACTTCC | PubMed | 4lg0_B(3.45e-03), 3wu1_AB(8.36e-03), 5zmc_B(6.27e-06) |
| GCCGGAA | PubMed | 4lg0_B(3.45e-03), 4lg0_AB(5.08e-03), 1k79_D(1.70e-04), ... (total=5) |
| AGTGCCGGAAATGT | PubMed | 4lg0_B(2.71e-04), 1k79_D(1.18e-07), 1k7a_A(2.03e-03), ... (total=4) |
Dendrogram of similar interfaces ?
matrix formatQCKTRGAT--RGNT---- L +-----------------------------8smh_F ! DCKTRGST--RGYA---- L --3 +4bnc_A ! +--------------------1 DCKTRG----RGYA--KA L +-------2 +5jvt_A ! ----NT--RGSTATRA-- L +---------------------2o6g_G |
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updated Sat Jan 10 07:13:43 2026