| structure name | STRUCTURE OF A TERNARY FOXO1-ETS1 DNA COMPLEX (PROTEIN C-ETS-1) |
| reference | Geiger et al. 'To ? ? ? |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=2.19, R-factor=0.197) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Etsdomain; |
| multimeric complexes | 3wu1_AB 4lg0_AB |
| redundant complexes |  1k79_D
1k7a_A
3wu1_B
5zmc_B
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKRRY |
Estimated binding specificities ?
| contact |  |
A | 69 0 0 87 69 69 C | 8 0 0 8 11 8 G | 11 96 96 1 8 11 T | 8 0 0 0 8 8scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ETS-1 | ||
| AGGAAGT | PubMed | 4lg0_B(6.54e-06), 3wu1_AB(5.07e-05), 4lg0_AB(1.06e-03), ... (total=4) |
| TTTTTAT | PubMed | 4lg0_AB(5.39e-03) |
| GAGGAATG | PubMed | 4lg0_B(1.83e-05), 4lg0_AB(4.39e-03), 5zmc_B(6.36e-03) |
| GACTTCC | PubMed | 4lg0_B(3.45e-03), 3wu1_AB(8.36e-03), 5zmc_B(6.27e-06) |
| GCCGGAA | PubMed | 4lg0_B(3.45e-03), 4lg0_AB(5.08e-03), 1k79_D(1.70e-04), ... (total=5) |
| AGTGCCGGAAATGT | PubMed | 4lg0_B(2.71e-04), 1k79_D(1.18e-07), 1k7a_A(2.03e-03), ... (total=4) |
Dendrogram of similar interfaces ?
matrix format------------KT--RG--RGYA---- L +-----------------------------3wts_C +-3 ----------DCKT--RG--RGYA---- L ! ! +-----------1dux_F +-4 +-----------------1 ------------------NTCT--NGST L ! ! +-----------1if1_B +-5 ! ----------------TT--CT--NGKG L ! ! +-----------------------------7oot_B +-6 ! RC-------------------------- ! ! +-----------------------------6l9z_S ! ! ----------------TT--CT--NGKG L --7 +-----------------------------7rh2_B ! ----LTNTHG--RTYTPT---------- L ! +-------------6qil_A +---------------2 --RC------------------------ +-------------7cow_T |
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updated Fri Sep 13 18:28:12 2024