5y36_A : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF SPCAS9-SGRNA-DNA TERNARY COMPLEX (CRISPR-ASSOCIATED ENDONUCLEASE CAS9CSN1)
source	STREPTOCOCCUS PYOGENES SEROTYPE M1
experiment	NMR
multimeric complexes	7v59_BE
redundant complexes	4oo8_D 4un3_B 5b2r_B 5b2s_B 5b2t_B 5f9r_B 5fw1_B 5fw2_B 5fw3_B 6aeb_F 6aeg_B 6ai6_A 6k3z_B 6k4p_B 6k4q_B 6k4s_B 6k4u_B 6k57_B 6o0z_A 7ox7_B 7ox8_B 7ox9_B 7oxa_B 7qqo_B 7qqp_B 7qqq_B 7qqr_B 7qqs_B 7qqt_B 7qqu_B 7qqv_B 7qqw_B 7qqx_B 7qqz_B 7qr0_B 7qr1_B 7qr5_B 7qr7_B 7qr8_B 7s36_P 7s38_P 7s3h_P 7s4u_A 7s4v_A 7v59_E 7z4c_B 7z4d_E 7z4e_B 7z4g_B 7z4h_B 7z4i_B 7z4k_B 7z4l_B 7zo1_B 8fzt_E 8g1i_A 8kah_B 8kai_F 8kaj_B 8kak_B 8kal_B 8kam_B 8t6o_A 8t6p_A 8t6s_A 8t6t_A 8t6x_A 8t6y_A 8t76_A 8t77_A 8t78_A 8t79_A 8t7s_G 6vpc
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5y36_A interface=64,67,71,75,167,169,405,447,450,766,772,866,908,909,911,912,914,919,920,960,964,975,976,977,980,982,1003,1004,1021,1022,1024,1034,1036,1037,1040,1041,1044,1108,1311,1313,1314,1317,1320,1322,1333,1335,1337, mdkkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrLkrTarrRytrRknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrgHfLiegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtFdngsiphqihlgelhailrrqedfypflkdnrekiekiltfRipYyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvsgqgdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarEnqttqKgqknsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgKsdnvpseevvkkmknywrqllnaklitqrkfdnltkaerggLSeLDkAgfikRQlvetrqitkhvaqildsrmntkydendklirevkvitlkSklvSdfrkdfqfykVREinNyHhahdaylnavvgtalikkypKLesefvygdykvydvrkMIaKseqeigkatAkYFfySNimNffkteitlangeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfskEsilpkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagelqkgnelalpskyvnflylashyeklkgspedneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniiHlFTltNlgApAafkyfdttidRkRyTstkevldatlihqsitglyetridlsqlggd
interface signature	LTRRHLFRYEKKLSLDARQSSVRENHKLMIKAYFSNNEHFTNAARRT

Estimated binding specificities ?

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# IC=20.085 IC/col=0.803 n_of_columns=25

specificity:

A |  96  24   0   0  24   0   9  24  84   6  24  24   0   0   0   0  96   0   0  24   9  24  68   0   0
C |   0  24  96   0  24   0  68  24   4   4  24  24   0   0   5  96   0   0   0  24   9  24   9  96  96
G |   0  24   0  96  24   0  10  24   4  82  24  24  96   0   0   0   0   0  96  24  65  24   9   0   0
T |   0  24   0   0  24  96   9  24   4   4  24  24   0  96  91   0   0  96   0  24  13  24  10   0   0

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updated Fri Sep 13 20:58:08 2024