interface graph thumbnail
legend  pdf

structure nameSOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, RESTRAINED REGULARIZED MEAN STRUCTURE
experimentNMR
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
redundant complexes2stt
reference complex2stt_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureERRY

Estimated binding specificities ?

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# IC=3.417 IC/col=0.854 n_of_columns=4 specificity:   
A |   1   0   7  10
C |  92  96   7  13
G |   1   0  74  63
T |   2   0   8  10
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----KTRG----RGYA--------   L                                 +--3wts_C    
                                                     +---------4 
  ----KTRG----RGYA--------   L                       !         +--4lg0_B    
                                          +----------7 
  --DCKTRG----RGYA----KA--   L            !          !           +5jvt_A    
                                       +-11          +-----------2 
  --DCKTRGST--RGYA--------   L         !  !                      +4bnc_A    
                                       !  !  
  ----KTRG----RAYA--------   L         !  +-----------------------6vge_A    
                                       !  
  --ECKTRGAT--RGNT--------   L         !                        +1pue_E    
                                       !                +-------3 
  --DCKTRG----RGYA--------   L      +-12           +----6       +3zp5_A    
                                    !  !           !    ! 
  ------NT--RGCT--NGST----   L      !  !  +--------8    +--------1if1_B    
                                    !  !  !        ! 
  --DCKTRG----RGYA--------   L      !  !  !        !            +1dux_F    
                                    !  !  !        +------------1 
  ----KTRGAT--RGYA--------   L      !  +-10                     +4iri_A    
                                 +-13     !  
  ----KTRGAT--RGYT--------   L   !  !     !                 +----1awc_A    
                                 !  !     !  +--------------5 
  --EAKTRGAT--RGYA------RT   L   !  !     +--9              +----3jtg_A    
                               -14  !        ! 
  ----ST------RTQT--KG----       !  !        +-------------------5d5w_B    
                                 !  !  
  --KG--ATNT--CT----SC----   L   !  +----------------------------2irf_L    
                                 !  
  NT----------------------       +-----------------------------7tve_F    
                               

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updated Thu Sep 12 16:32:43 2024