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structure nameGR DNA BINDING DOMAIN:FKBP5 BINDING SITE COMPLEX-9
(Glucocorticoid receptor)
referenceYamamoto et al. Science 324 407 2009
sourceRattus norvegicus
experimentX-ray (resolution=2.26, R-factor=0.176)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1glu_AB 1r4o_AB 1r4r_AB 3fyl_AB 3g6p_AB 3g6q_AB 3g6r_AB 3g6u_AB 3g8u_AB 3g8x_AB 3g97_AB 3g99_AB 3g9i_AB 3g9j_AB 3g9m_AB 3g9o_AB 3g9p_AB 5va0_AB 5va7_AB 6bse_AB 6x6d_AB 6x6e_AB
reference complex3g9m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0   0  13  24  13
C |   0   0  16  24  54
G |   0  96  13  24  13
T |  96   0  54  24  16
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updated Mon Dec 16 20:51:35 2024