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structure nameGR GAMMA DNA-BINDING DOMAIN:FKBP5 16BP COMPLEX-34
(Glucocorticoid receptor)
referenceYamamoto et al. Science 324 407 2009
sourceRattus norvegicus
experimentX-ray (resolution=1.90, R-factor=0.181)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1glu_AB 1r4o_AB 1r4r_AB 3fyl_AB 3g6p_AB 3g6q_AB 3g6r_AB 3g6t_AB 3g6u_AB 3g8u_AB 3g8x_AB 3g97_AB 3g99_AB 3g9i_AB 3g9j_AB 3g9m_AB 3g9o_AB 3g9p_AB 4hn5_AB 4hn6_AB 5cbx_AB 5cbx_EF 5cby_AB 5cc1_AB 5cc1_WX 5e69_AB 5e6a_AB 5e6b_AB 5e6c_AB 5emc_AB 5emp_AB 5emq_AB 5va0_AB 5va7_AB 6bse_AB 6x6d_AB 6x6e_AB
reference complex3g9m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVRK

Estimated binding specificities ?

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# IC=3.964 IC/col=0.661 n_of_columns=6 specificity:   
A |   0   0   9  24  19   9
C |   0   0   9  24  67   9
G |   0  96   9  24   1  21
T |  96   0  69  24   9  57
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updated Thu Jan 8 21:33:32 2026