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structure nameGLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - RELB NF-KB RESPONSE ELEMENT COMPLEX
(Glucocorticoid receptor)
referenceOrtlund et al. 'Nat 9 1337 2018
sourceHomo sapiens
experimentX-ray (resolution=2.25, R-factor=0.206)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1glu_AB 1r4o_AB 1r4r_AB 3fyl_AB 3g6p_AB 3g6q_AB 3g6r_AB 3g6t_AB 3g6u_AB 3g8u_AB 3g8x_AB 3g97_AB 3g99_AB 3g9i_AB 3g9j_AB 3g9m_AB 3g9o_AB 3g9p_AB 4hn5_AB 4hn6_AB 5cbx_AB 5cbx_EF 5cby_AB 5cc1_AB 5cc1_WX 5e69_AB 5e6a_AB 5e6b_AB 5e6c_AB 5emc_AB 5emp_AB 5emq_AB 5va0_AB 5va7_AB 6bse_AB 6x6d_AB 6x6e_AB
reference complex3g9m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=2.490 IC/col=0.498 n_of_columns=5 specificity:   
A |   8  24  69   8   0
C |  11  24  11  11   8
G |  69  24   8   8   0
T |   8  24   8  69  88
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updated Fri Jan 9 03:12:38 2026