interface graph thumbnail
legend  pdf

structure nameGLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - RELB NF-KB RESPONSE ELEMENT COMPLEX
(Glucocorticoid receptor)
referenceOrtlund et al. 'Nat 9 1337 2018
sourceHomo sapiens
experimentX-ray (resolution=2.25, R-factor=0.206)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=2.527 IC/col=0.505 n_of_columns=5 specificity:   
A |  87  69   8  24   8
C |   0   8   8  24  69
G |   0  11   8  24  11
T |   9   8  72  24   8
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updated Tue Dec 17 01:35:09 2024