interface graph thumbnail
legend  pdf

structure nameGLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN - RELB NF-KB RESPONSE ELEMENT COMPLEX
(Glucocorticoid receptor)
referenceOrtlund et al. 'Nat 9 1337 2018
sourceHomo sapiens
experimentX-ray (resolution=2.25, R-factor=0.206)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes4hn6_AB 5cc1_AB 5cc1_WX 5e69_AB 5e6a_AB 5e6b_AB 5e6c_AB
reference complex5e69_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=2.563 IC/col=0.513 n_of_columns=5 specificity:   
A |   8  24  69   8   0
C |   8  24   8   8   8
G |  72  24   8   8   1
T |   8  24  11  72  87
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updated Thu Sep 12 21:12:04 2024